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Safety Precautions and Operating Procedures in an ABSL-4 Laboratory: 3. Aerobiology
Published on: October 3, 2016
[Bioterrorism and pathogenic microorganisms]
Hermann G Schatzmayr, Ortrud Monika Barth1
1Laboratório de Morfologia e Morfogênese Viral, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Brasil, Rio de JanerioRJ, Pesquisadora do Laboratório de Morfologia e Morfogênese Viral/Instituto Oswaldo Cruz/Fundação Oswaldo Cruz. Av. Brasil, 4365/Pavilhão Hélio e Peggy Pereira 21040-900 - Rio de Janerio - RJ - Brasil.barth@ioc.fiocruz.br.
Abstract:
In recent years the use of pathogenic microorganisms in acts of bioterrorism has been the subject of major concern in many countries. This paper presents a possible application of viruses and bacteria for warfare and terrorist purposes, as well as a laboratory diagnosis to identify those agents. The viruses of smallpox (orthopoxvirus), of hemorrhagic fever and those belonging to filovirus have been highlighted, inter alia, as agents of human infection with bioterrorist intent. Among the bacteria, the emphasis has been on anthrax (Bacillus anthracis), the plague (Yersinia pestis), botulism (Clostridium botulinum) and tularemia (Francisella tularensis), not to mention ricin (Ricinus communis), as one of the Group B agents.
Insights
Bioterrorism threats involve pathogenic viruses like smallpox and filoviruses, and bacteria such as anthrax and plague. This paper discusses their use and laboratory diagnosis for identification.
Area of Science:
- Microbiology
- Virology
- Pathogen research
Context:
- Bioterrorism poses a significant global security threat.
- Pathogenic microorganisms are potential agents for warfare and terrorism.
Purpose:
- To outline the potential application of specific viruses and bacteria in bioterrorism.
- To describe laboratory diagnostic methods for identifying these agents.
Summary:
- Highlights viruses like smallpox (orthopoxvirus), hemorrhagic fever viruses, and filoviruses as bioterrorist agents.
- Focuses on bacteria including Bacillus anthracis (anthrax), Yersinia pestis (plague), Clostridium botulinum (botulism), and Francisella tularensis (tularemia).
- Mentions ricin (Ricinus communis) as a notable Group B agent.
Impact:
- Informs on key biological agents relevant to bioterrorism preparedness.
- Underscores the importance of robust laboratory diagnostic capabilities for national security.
- Provides a foundational overview for further research into pathogen detection and defense strategies.
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