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Lack of difference between continuous versus intermittent heparin infusion on maintenance of intra-arterial catheter

Maria Carolina Witkowski1, Maria Antonieta P de Moraes2, Cora Maria F Firpo2

  • 1Hospital de Clínicas de Porto Alegre, Porto AlegreRS, Brasil.

Revista Paulista De Pediatria : Orgao Oficial Da Sociedade De Pediatria De Sao Paulo
|January 30, 2014
PubMed

Insights

Both continuous and intermittent heparin infusions effectively maintain arterial catheters in pediatric surgery patients. Intermittent infusion uses less heparin, a consideration for underweight children.

Area of Science:

  • Pediatric Surgery
  • Vascular Access Management
  • Pharmacology

Background:

  • Arterial catheters are crucial for hemodynamic monitoring in pediatric surgery.
  • Maintaining catheter patency with heparin is standard practice.
  • Different heparin infusion methods exist, each with potential benefits and risks.

Purpose of the Study:

  • To compare continuous infusion group (CIG) and intermittent infusion group (IIG) for arterial catheter maintenance in pediatric surgery.
  • To analyze adverse events related to catheter insertion site and heparin volume.
  • To evaluate the efficacy and safety of two heparin maintenance systems.

Main Methods:

  • Randomized controlled trial involving 140 pediatric patients.
  • Analysis of variables including catheter dwell time, insertion site, and heparin volume.
  • Statistical analysis using Student's t-test and chi-square test (p<0.05).

Main Results:

  • No significant differences in adverse events between CIG and IIG.
  • Significantly lower heparin volume used in IIG (5.3±3.5mL/24h) compared to CIG (12.0±1.2mL/24h; p<0.0003).
  • Demographic and clinical characteristics did not influence outcomes.

Conclusions:

  • Both continuous and intermittent heparin infusion systems are viable for arterial catheter maintenance in pediatric surgery.
  • Intermittent infusion may be preferable for underweight children due to reduced heparin volume.
  • Adverse events were comparable across both groups in the early postoperative period.
Abstract

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