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Updated: May 3, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Amelanotic metastatic cutaneous melanoma
Marcela Sena Teixeira Mendes1, Mariana Carvalho Costa2, Ciro Martins Gomes3
1Dermatology service, Brasilia University Hospital, Brasilia University, BrasíliaDF, Brazil, MD, Resident of the Dermatology service at Brasilia University Hospital - Brasilia University (HUB-UnB) - Brasília (DF), Brazil.
Abstract:
Dermatoscopy of melanocytic lesions has guided the decision of when or not to biopsy a lesion. The use of this tool has increased clinical examination's sensitivity and specificity in 89% and 96% respectively. However, dermatoscopic evaluation of amelanotic or hypomelanotic melanomas, as well as metastases, can be difficult. There is still no standardization for the analysis of these pathologies, which relies mostly on their vascular pattern. We describe the dermatoscopy of acral metastatic amelanotic melanoma.
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