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Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
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Rabies Necropsy Techniques in Large and Small Animals
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UK veterinary schools: emphasis on end-of-life issues

G E Dickinson1, E S Paul

  • 1Department of Sociology and Anthropology, College of Charleston, 66 George Street, Charleston, SC 29424, USA.

The Veterinary Record
|January 31, 2014
PubMed
Summary

No abstract available in PubMed .

Keywords:
EthicsPreclinical educationVeterinary profession

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