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Related Concept Videos

Bone Disorders01:29

Bone Disorders

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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
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The Bone Matrix01:18

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Bone contains a relatively small number of cells entrenched in a matrix of collagen fibers that provide an adherent surface for inorganic salt crystals. Both components of the matrix, organic and inorganic, contribute to the unusual properties of bone. Without collagen, bones would be brittle and shatter easily. Without mineral crystals, bones would flex and provide little support. This can be observed by an experiment: when the minerals of a bone are dissolved by soaking the bone in...
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Essential Minerals for Bone Health01:31

Essential Minerals for Bone Health

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The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
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Role of Vitamins in Maintaining Bone Health01:25

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The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
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Blood and Nerve Supply to the Bones01:29

Blood and Nerve Supply to the Bones

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Bones are dynamic organs that require a rich supply of oxygen and nutrients. Around 5% to 10% of the cardiac output supplies blood to the bones. A typical long bone has three main sources: the nutrient artery, the metaphyseal and epiphyseal arteries, and the periosteal arteries.
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
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Bone as Supporting Connective Tissue01:23

Bone as Supporting Connective Tissue

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Bone tissue forms the internal skeleton of vertebrate animals, providing structure to the body.
Bone Matrix
Bone, or osseous tissue, is a connective tissue that has a large amount of two different types of matrix material. The organic matrix is similar to the matrix material found in other connective tissues, including some amount of collagen and elastic fibers. This gives strength and flexibility to the tissue. The inorganic matrix consists of mineral salts— mostly calcium salts—...
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Alcohol and bone.

Peter Mikosch1

  • 1Ludwig Boltzmann Institute of Osteology at the Hanusch Hospital of WGKK and AUVA Trauma Centre Meidling,1st Medical Department, Hanusch Hospital, Heinrich Collin Str. 30, 1140, Vienna, Austria, Peter.Mikosch@osteologie.at.

Wiener Medizinische Wochenschrift (1946)
|January 31, 2014
PubMed
Summary
This summary is machine-generated.

Heavy alcohol consumption, including binge drinking, significantly harms bone health, increasing osteoporosis risk. Lifestyle factors associated with alcoholism exacerbate bone density loss and weakness.

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Area of Science:

  • Bone Biology
  • Endocrinology
  • Public Health

Background:

  • Alcohol consumption is prevalent globally, with patterns ranging from light to heavy chronic use and binge drinking.
  • Heavy alcohol consumption negatively impacts multiple organs, notably bone tissue.
  • Osteoporosis is a recognized secondary consequence of alcoholism, with chronic abuse being an independent risk factor.

Purpose of the Study:

  • To review the mechanisms and effects of alcohol intake on bone mass, metabolism, and strength.
  • To explore the role of lifestyle factors in alcohol-induced osteoporosis.

Main Methods:

  • Literature review of studies investigating alcohol's impact on bone.
  • Analysis of mechanisms affecting bone density and quality.
  • Examination of contributing lifestyle and hormonal factors.

Main Results:

  • Chronic alcohol abuse detrimentally affects bone mass, metabolism, and strength.
  • Alcoholism-related factors like malnutrition, inactivity, and hormonal imbalances contribute to osteoporosis.
  • Binge drinking represents a significant pattern of alcohol consumption among young adults with potential bone health implications.

Conclusions:

  • Chronic alcohol consumption is a significant risk factor for osteoporosis.
  • Understanding the multifaceted effects of alcohol on bone is crucial for prevention and treatment strategies.
  • Lifestyle modifications and addressing hormonal changes are important in mitigating alcohol-related bone damage.