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Updated: May 3, 2026

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A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment
Published on: May 25, 2017
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Impact of changes in Clostridium difficile testing practices on stool rejection policies and C. difficile positivity
Jessica Cohen1, Brandi Limbago, Ghinwa Dumyati
1Atlanta Research and Education Foundation, Atlanta, Georgia, USA.
Journal of Clinical Microbiology
|January 31, 2014
Abstract:
We describe the adoption of nucleic acid amplification tests (NAAT) for Clostridium difficile diagnosis and their impact on stool rejection policies and C. difficile positivity rates. Of the laboratories with complete surveys, 51 (43%) reported using NAAT in 2011. Laboratories using NAAT had stricter rejection policies and increased positivity rates.

