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Diagnosing Pulmonary Tuberculosis with the Xpert MTB/RIF Test
Published on: April 9, 2012
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GeneXpert MTB/RIF version G4 for identification of rifampin-resistant tuberculosis in a programmatic setting
Muhammad Osman1, John A Simpson, Judy Caldwell
1City Health Directorate, City of Cape Town, South Africa.
Journal of Clinical Microbiology
|January 31, 2014
Abstract:
A recent Cochrane review estimated GeneXpert MTB/RIF specificity for rifampin resistance as 98% (95% confidence interval [CI], 97 to 99), based on results from earlier test versions. The measured positive predictive value of the new generation test from programmatic implementation in Cape Town, South Africa, was 99.5% (95% CI, 98.5 to 100), confirming excellent specificity.
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