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Related Concept Videos

Toxic Reactions: Overview01:26

Toxic Reactions: Overview

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When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive metabolites that may covalently bind with specific target molecules, resulting in toxicity.
Toxicity falls into two primary categories: local and systemic.
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Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
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Types of Toxins01:36

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Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
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Vegetated Treatment Systems for Removing Contaminants Associated with Surface Water Toxicity in Agriculture and Urban Runoff
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Revisiting endosulfan.

Dilip Gude1, Dharam Pal Bansal2

  • 1Department of Internal Medicine, Medwin Hospital, Nampally, Hyderabad, Andhra Pradesh, India.

Journal of Family Medicine and Primary Care
|January 31, 2014
PubMed
Summary
This summary is machine-generated.

Endosulfan poisoning poses severe health risks, potentially causing fatal multi-organ damage. This case highlights the extreme dangers of endosulfan toxicity, leading to cardiac arrest and death.

Keywords:
Endosulfanmulti-organ failureseizures

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Area of Science:

  • Toxicology
  • Environmental Health
  • Clinical Medicine

Background:

  • Endosulfan is an organochlorine pesticide with known toxic properties.
  • Exposure can lead to a range of adverse health effects, varying in severity.

Observation:

  • A case of acute endosulfan poisoning is presented.
  • The patient exhibited symptoms progressing to severe multi-organ dysfunction.

Findings:

  • The poisoning resulted in intractable seizures and multi-organ failure.
  • The case culminated in cardiac arrest and death.

Implications:

  • This case underscores the critical need for stringent regulation and safe handling of endosulfan.
  • Highlights the potential for severe, fatal outcomes from endosulfan exposure.
  • Emphasizes the importance of prompt medical intervention in pesticide poisoning cases.