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A Fish-feeding Laboratory Bioassay to Assess the Antipredatory Activity of Secondary Metabolites from the Tissues of Marine Organisms
Published on: January 11, 2015
A new diketopiperazine from the gorgonian coral Menella kanisa
Chenghai Gao1, Lin Lin, Bin Long
1a Guangxi Key Laboratory of Marine Environmental Science , Guangxi Academy of Sciences , Nanning 530-007 , P.R. China.
Abstract:
Chemical investigation on the gorgonian Menella kanisa collected from Beibu Gulf led to the isolation of a new diketopiperazine, named menazepine A (1), as well as three known diketopiperazines, namely cyclo(4-hydroxyprolylleucyl) (2), cyclo(Pro-Leu) (3) and cyclo(4-hydroxyprolylphenylalanyl) (4). The structure of the new diketopiperazine was elucidated on the basis of extensive spectroscopic analysis and by comparing the data with those of related metabolites. Compounds 1-4 were also evaluated for brine shrimp lethality.
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