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Antimicrobial resistance in eight US hospitals along the US-Mexico border, 2000-2006

S R Benoit1, K D Ellingson1, S H Waterman2

  • 1Division of Healthcare Quality Promotion,National Center For Emerging & Zoonotic Infectious Diseases,CDC, Atlanta, GA,USA.

Epidemiology and Infection
|February 1, 2014
PubMed

Insights

Antimicrobial resistance (AR) is increasing globally. This study found rising AR rates in common bacteria along the US-Mexico border, highlighting the need for further investigation into contributing factors.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Microbiology

Background:

  • Antimicrobial resistance (AR) poses a significant global health threat.
  • International travel and migration can facilitate the spread of AR.
  • Understanding regional AR patterns is crucial for effective control strategies.

Purpose of the Study:

  • To examine antimicrobial resistance rates and trends.
  • To analyze data along the US-Mexico border.
  • To identify key antimicrobial-pathogen combinations with increasing resistance.

Main Methods:

  • Analysis of microbiology data from eight US hospitals (2000-2006).
  • Focus on common Gram-negative (E. coli, P. aeruginosa, K. pneumoniae) and Gram-positive (S. aureus, Enterococcus, S. pneumoniae) pathogens.
  • Evaluation of 10 antimicrobial-pathogen resistance combinations.

Main Results:

  • Highest resistance observed in Staphylococcus aureus (oxacillin, 45.7%), Pseudomonas aeruginosa (quinolone, 22.3%), and Escherichia coli (quinolone, 15.6%).
  • Six out of ten (60%) antimicrobial-pathogen combinations showed a significant increasing resistance trend over the study period.
  • Specific resistance patterns identified in key pathogens.

Conclusions:

  • Antimicrobial resistance is a growing concern along the US-Mexico border.
  • Increasing resistance trends necessitate further investigation into local factors.
  • Exploring infection control and antimicrobial use in the region is recommended.

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