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Cardiothoracic interventions in Behçet's disease.

Shi-Min Yuan1

  • 1The First Hospital of Putian, Teaching Hospital, Fujian Medical University, Putian, China. shi_min_yuan@yahoo.com.

Clinical and Experimental Rheumatology
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Cardiothoracic interventions for Behçet's disease cardiovascular complications are detailed, with cardiac surgery being most common. High rates of postoperative complications and recurrence were observed, particularly prosthetic valve dehiscence.

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Area of Science:

  • Cardiology
  • Thoracic Surgery
  • Vascular Surgery

Background:

  • Behçet's disease is a rare multisystemic inflammatory disorder.
  • Cardiovascular complications are a significant cause of morbidity and mortality in Behçet's disease.
  • Limited data exists on cardiothoracic interventions for these complications.

Purpose of the Study:

  • To elucidate the role and outcomes of cardiothoracic interventions for cardiovascular complications of Behçet's disease.
  • To analyze the types of procedures, indications, and complication rates.
  • To identify factors influencing outcomes.

Main Methods:

  • A comprehensive literature search was conducted for studies published between 2000 and 2013.
  • Articles focusing on cardiothoracic procedures for cardiovascular complications of Behçet's disease were screened and analyzed.
  • Data on procedure types, indications, postoperative outcomes, and recurrence were extracted.

Main Results:

  • A total of 221 major cardiothoracic procedures were analyzed, with cardiac operations (79.6%) being most frequent.
  • Common indications included aortic valve regurgitation, pulmonary artery aneurysm, and thrombosis.
  • High postoperative morbidity (21.4%), recurrence (11.7%), and mortality (15.0%) rates were reported.
  • Prosthetic valve dehiscence was the leading cause of morbidity and mortality.

Conclusions:

  • Cardiovascular operations are prevalent for Behçet's disease complications, often involving valve, aneurysm, or thrombotic issues.
  • Postoperative complications and recurrence rates are substantial.
  • Intensified immunosuppressive therapy may mitigate postoperative complications and reintervention needs.