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Updated: May 3, 2026

Orthotopic Mouse Model of Colorectal Cancer
Published on: December 4, 2007
Orbital metastasis as the inaugural presentation of occult rectal cancer
Eya Cherif1, Lamia Ben Hassine, Samira Azzabi
1Faculty of Medicine, Department of Internal Medicine, Charles Nicolle's Hospital, University of Tunis El Manar, Tunis, Tunisia.
Abstract:
Orbital metastasis is uncommon and occurs in 2-3% of patients with cancer. It is rarely the initial manifestation of a systemic malignancy. It usually indicates extensive haematogenous dissemination of a primary cancer and is associated with poor prognosis. Breast, lungs and prostate cancers are the most common primary cancers leading to orbital metastasis. However, orbital tumour revealing a rectal adenocarcinoma is exceptional. We describe a case of orbital tumour in a 67-year-old man with no history of systemic cancer while presenting with ophthalmic symptoms. Investigations revealed rectal adenocarcinoma as the primary malignant tumour.
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