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Cerebral microbleeds and fatigue in stroke.
Wai Kwong Tang1, Xiang Xin Liu, Yang Kun Chen
1Department of Psychiatry, Chinese University of Hong Kong, Hong Kong, SAR, PR China.
European Neurology
|February 1, 2014
Summary
Poststroke fatigue (PSF) is common after stroke. This study found that deep cerebral microbleeds (CMBs) are linked to a higher risk of developing poststroke fatigue.
Area of Science:
- Neurology
- Neuroimaging
- Stroke Medicine
Background:
- Poststroke fatigue (PSF) is a prevalent and enduring issue for stroke survivors.
- The underlying neuroanatomical mechanisms of PSF are not well understood.
Purpose of the Study:
- To investigate the association between poststroke fatigue and cerebral microbleeds (CMBs).
Main Methods:
- 199 patients with acute ischemic stroke were assessed.
- Fatigue Severity Scale (FSS) was used to define PSF (FSS score ≥ 4.0).
- Cerebral microbleeds (CMBs) were identified using magnetic resonance imaging within 7 days of admission.
Main Results:
- 23.6% of patients experienced PSF.
- The PSF group showed a higher Geriatric Depression Scale score and a trend towards older age.
- Deep CMBs were significantly more prevalent in patients with PSF (66.0% vs. 48.7%).
Conclusions:
- Deep CMBs are associated with an increased risk of poststroke fatigue.
- Further research is required to understand the impact of CMBs on PSF presentation, treatment, and outcomes.
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