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Updated: May 3, 2026
05:39
Spontaneous Murine Model of Anaplastic Thyroid Cancer
Published on: February 3, 2023
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[Differentiated thyroid cancer: an ancient disease with new knowledge]
Martín Granados García1, Alberto Mitsuo León Takahashi, Francisco Javier Guerrero Huerta
1Servicio de Cabeza y Cuello, Instituto Nacional de Cancerología, México, D.F. takabeto18@hotmail.com.
Gaceta Medica De Mexico
|February 1, 2014
Summary
Differentiated thyroid cancer, a rising endocrine malignancy, is increasingly complex due to multidisciplinary care. Advances in genetics and molecular biology are improving treatment for iodine-refractory cases.
Area of Science:
- Endocrinology
- Oncology
Context:
- Differentiated thyroid cancer (DTC) is the most common endocrine malignancy.
- Its incidence is rising rapidly, yet it generally has a good prognosis.
- Multidisciplinary care has evolved treatment focus and introduced controversies.
Purpose:
- To review and update knowledge on differentiated thyroid cancer.
- To discuss treatment guidelines based on prognostic factors, treatment effects, and comorbidities.
- To highlight recent advances in genetics, molecular biology, and adjuvant therapies.
Summary:
- Treatment guidelines for DTC are based on prognostic factors, treatment effects, and comorbidities due to a lack of controlled trials.
- Recent advances include applying genetics and molecular biology to iodine-refractory disease.
- The use of tracers and recombinant hormones has improved adjuvant treatment.
Impact:
- Provides an updated review of differentiated thyroid cancer, an ancient disease.
- Informs clinicians on current treatment strategies and emerging therapies.
- Highlights the impact of genetic and molecular advancements on managing refractory thyroid cancer.
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