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Published on: November 7, 2018
Laribacter hongkongensis: an emerging pathogen of infectious diarrhea
M Krishna Raja1, Asit Ranjan Ghosh
1Centre for Infectious Diseases and Control, School of Bio Sciences and Technology, VIT University, Vellore, 632014, India.
Abstract:
Laribacter hongkongensis is relatively a new name in the list of bacterial pathogens for gastroenteritis and travelers' diarrhea. Addition of another name increases burden on the enteric infections as a whole. L. hongkongensis belongs to Neisseriaceae family of β subclass Proteobacteria. L. hongkongensis was initially isolated in Hong Kong from blood and empyema of an alcoholic cirrhotic patient in 2001, followed by reports from Korea and China, representing a total of 38 articles in PubMed until April 2013. As of now, there is no report from Indian subcontinent where infectious diarrhea is very much prevalent and a major burden. This review provides information about the microbiological characteristics, consideration of an emerging pathogen, relative pathogenicity, genome and proteome content, resistance toward multiple antibiotics, adaptability to different stress, and other features since its time of discovery. Investigation for this bacterium may avoid misidentification as other microbial flora. Further studies like the geographical distribution, type of infection, disease burden, pathogenicity, or genomic exploration of this bacterium will be useful in characterizing them properly. This bacterium may possibly be the emerging threat to public health.
Insights
Laribacter hongkongensis is an emerging bacterial pathogen causing gastroenteritis. Further research is needed to understand its geographical distribution and pathogenicity, especially in regions like the Indian subcontinent.
Area of Science:
- Microbiology
- Infectious Diseases
- Bacteriology
Background:
- Laribacter hongkongensis is a recently identified bacterial pathogen.
- It belongs to the Neisseriaceae family within the β subclass Proteobacteria.
- First isolated in Hong Kong in 2001, it has been reported in Korea and China.
Purpose of the Study:
- To review the microbiological characteristics of Laribacter hongkongensis.
- To assess its potential as an emerging pathogen.
- To consolidate information on its pathogenicity, genome, and antibiotic resistance.
Main Methods:
- Literature review of studies on Laribacter hongkongensis.
- Analysis of reported cases and microbiological data.
- Examination of genomic and proteomic information.
Main Results:
- Laribacter hongkongensis causes gastroenteritis and travelers' diarrhea.
- The bacterium exhibits resistance to multiple antibiotics.
- It demonstrates adaptability to various stress conditions.
Conclusions:
- Laribacter hongkongensis is a potential emerging threat to public health.
- Further studies are required to determine its geographical distribution and disease burden.
- Accurate identification is crucial to avoid misdiagnosis.
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