Reproductive outcomes after resection of intrauterine septum

Pre-and post-septal resection reproductive outcomes were compared in women with infertility and prior pregnancy losses operated on for uterine septum from 2003 to 2010. The major indications for surgery were primary infertility (n = 41, 33.1%), secondary infertility (n = 21, 16.9%) and prior pregnancy losses (n = 52, 41.9%). A total of 74 women (59.7%) had an incomplete septum and 50 (40.3%) had a complete septum. Re-hysteroscopy was done in two women (1.6%); 40 (32.3%) women were lost to follow-up after resection; 63 of the remaining 84 (75.0%) conceived and there were a total of 98 pregnancies. A cerclage was done in 28 (32.9%) of these pregnancies. Miscarriage and live birth rates were 92.9% and 4.1% pre- and 32.1% and 61.2% post-resection, respectively. Hysteroscopic septal resection significantly improves reproductive performance in women with infertility and prior pregnancy losses.