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Meloxicam pharmacokinetics using nonlinear mixed-effects modeling in ferrets after single subcutaneous administration

S K Chinnadurai1, K M Messenger, M G Papich

  • 1Environmental Medicine Consortium, North Carolina State University College of Veterinary Medicine, Raleigh, NC, USA; Department of Clinical Sciences, North Carolina State University College of Veterinary Medicine, Raleigh, NC, USA; Department of Molecular Biomedical Sciences, North Carolina State University College of Veterinary Medicine, Raleigh, NC, USA.

Journal of Veterinary Pharmacology and Therapeutics
|February 4, 2014
PubMed
Summary

This study examined meloxicam pharmacokinetics in ferrets, finding significant sex differences in drug absorption and elimination. These pharmacokinetic variations between male and female ferrets are crucial for effective meloxicam dosing.

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