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Cardiac cavernous hemangioma and multiple pulmonary cavernous hemangiomas

Lili Yang1, Jun Dai1, Ying Xiao1

  • 1Institute of Pathology of Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

The Annals of Thoracic Surgery
|February 4, 2014
PubMed

Insights

This study reports the first documented case of cardiac cavernous hemangioma coexisting with multiple pulmonary cavernous hemangiomas, highlighting a rare vascular anomaly in both the heart and lungs.

Area of Science:

  • Cardiovascular Pathology
  • Pulmonary Medicine
  • Oncology

Background:

  • Cavernous hemangiomas are benign vascular tumors typically found in the liver or skin.
  • Cardiac and pulmonary cavernous hemangiomas are exceptionally rare, with limited case reports.

Observation:

  • A patient presented with symptoms suggestive of cardiac and pulmonary disease.
  • Imaging studies revealed bilateral pulmonary nodules, pericardial effusion, and a pericardial neoplasm.
  • Pathological examination confirmed large, blood-filled vascular spaces consistent with cavernous hemangiomas in both the heart and lungs.

Findings:

  • The cardiac tumor and pulmonary nodules exhibited characteristic features of cavernous hemangiomas.
  • Immunohistochemical markers (CD31, FLI1, FVIII, CD34) confirmed endothelial cell origin.
  • This represents the first reported instance of coexisting cardiac and multiple pulmonary cavernous hemangiomas.

Implications:

  • This case expands the known spectrum of cavernous hemangioma presentation.
  • Highlights the importance of considering rare vascular tumors in differential diagnoses for cardiac and pulmonary lesions.
  • Further research may elucidate the underlying mechanisms and potential genetic factors of multifocal cavernous hemangiomas.

Keywords:
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