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Micronutrient status in type 2 diabetes: a review
Bhupinder Kaur1, Jeyakumar Henry1
1Clinical Nutrition Research Centre, Singapore Institute for Clinical Sciences, Singapore, Singapore.
Advances in Food and Nutrition Research
|February 4, 2014
Summary
Type 2 diabetes impacts micronutrient levels, affecting trace minerals and vitamins. Supplementation may aid glycemic control, but more research is needed for optimal nutrient requirements.
Area of Science:
- Endocrinology
- Nutritional Science
- Metabolic Disorders
Background:
- Type 2 diabetes (T2D) is associated with significant micronutrient depletion.
- Metabolic derangements and complications in T2D contribute to altered nutrient metabolism.
- This review focuses on less-studied micronutrients beyond vitamin D.
Purpose of the Study:
- To review the micronutrient status in type 2 diabetes.
- To assess metabolic needs and potential requirements of specific micronutrients.
- To evaluate the current evidence on micronutrient supplementation for glycemic control.
Main Methods:
- Literature review and synthesis of existing evidence.
- Focus on trace minerals (zinc, magnesium, chromium, copper, manganese, iron, selenium, vanadium) and B-group vitamins.
- Exclusion of vitamin D due to extensive prior reviews.
Main Results:
- Evidence suggests altered metabolism of key trace minerals and vitamins in T2D.
- Some studies indicate a positive impact of micronutrient supplementation on glycemic control.
- Optimal supplementation levels and biomarkers for T2D patients require further investigation.
Conclusions:
- Micronutrient status is a critical, yet under-explored, aspect of type 2 diabetes management.
- Further research is essential to establish precise micronutrient requirements and effective supplementation strategies.
- Achieving glucose homeostasis through targeted micronutrient intervention remains a significant challenge.
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