Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Asymmetric Lipid Bilayer01:35

Asymmetric Lipid Bilayer

8.0K
Biological membranes show uneven distribution of different types of lipids in the inner and outer layers, resulting in transverse asymmetric membranes. The treatment of the erythrocyte membrane with the enzyme phospholipase confirmed the asymmetric nature of the lipid bilayer. The enzyme hydrolyzes lipids into fatty acids and hydrophilic groups. The phospholipase acts only on the outer layer of the membrane, while the inner layer remains intact. The phospholipase treatment resulted in 80%...
8.0K
Molecular Factors Affecting Cell Division01:27

Molecular Factors Affecting Cell Division

3.9K
Several external and internal factors influence the initiation and inhibition of cell division. For instance, the death of nearby cells or the release of human growth hormone (hGH) promotes cell division. In contrast, lack of hGH or crowding of cells can inhibit cell division.
Several proteins function as internal regulators to ensure each cell cycle stage is completed faithfully before proceeding to the next. Regulator molecules may act directly or influence the activity or production of other...
3.9K
Distribution of Cytoplasmic Content02:33

Distribution of Cytoplasmic Content

3.3K
Cytokinesis segregates a cell’s chromosomes and organelles into its daughter cells. Organelles divide and grow prior to cell division but cannot be synthesized de novo; therefore, cells must receive at least one copy of each organelle to survive. Currently, many of the details of how the organelles are distributed are not yet fully elucidated.
Distribution of cytoplasmic determinants
The cytoplasm contains various organelles, as well as salts, proteins, and water. The distribution of...
3.3K
Biosynthesis of Lipids01:29

Biosynthesis of Lipids

961
Microbial membranes exhibit remarkable diversity in lipid composition, reflecting evolutionary adaptations to various environmental conditions. The three domains of life—Bacteria, Archaea, and Eukarya—synthesize membrane lipids through distinct biosynthetic pathways, leading to fundamental structural differences that impact membrane stability, function, and adaptability.Fatty Acid-Based Lipids in Bacteria and EukaryaBacteria and eukaryotes share a common fatty acid biosynthesis...
961
Assembly of the Lipid Bilayer in the ER01:28

Assembly of the Lipid Bilayer in the ER

3.2K
Biological membranes are more than just a barrier separating cell cytoplasm from the outside environment. They are highly dynamic and help maintain the integrity and physiological stability of the cells as well as membrane-bound organelles. Membranes also play vital roles in cell-to-cell and intracellular communication.
A large chunk of any biological membrane is composed of phospholipids. These lipids have a heterogeneous distribution across different subcellular organelles and even between...
3.2K
Membrane Domains01:18

Membrane Domains

6.2K
The membrane domains concentrate specific lipids and proteins at one place within the membrane, which helps in cell signaling, adhesion, and other critical cellular processes. These domains can differ in size, composition, function, and lifespan.
Protein Domains
The membrane comprises a group of distinct proteins responsible for carrying out a cell's specific function. For example, the plasma membrane of the human sperm, or a single germ cell, contains a unique set of proteins in the...
6.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Diagnostic Accuracy of Lateral Flow Blood Tests to Detect Large Vessel Occlusion Stroke.

Stroke (Hoboken, N.J.)·2026
Same author

A Multi-scale Interfacial Investigation of Organic Friction Modifiers in Hydrocarbon.

Tribology letters·2026
Same author

Novel predictors of major adverse cardiovascular events in patients with Takotsubo cardiomyopathy: a contemporary analysis.

Internal medicine journal·2025
Same author

SiR-XActin: A Fluorescent Probe for Imaging Actin Dynamics in Live Cells.

Angewandte Chemie (International ed. in English)·2025
Same author

The Burgess blueprint: Love, leadership, and lifelong learning in infectious diseases pharmacy.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists·2025
Same author

[A new player in the budding process of the AIDS virus].

Medecine sciences : M/S·2025
Same journal

A viral ORFeome library for systems-level genetic dissection of host-pathogen interactions.

Cell·2026
Same journal

Co-option of lysosomal machinery shapes the evolution of the intracellular photosymbiosis supporting coral reefs.

Cell·2026
Same journal

LEF1 and niche factors determine T cell stemness across chronic diseases.

Cell·2026
Same journal

Recurrent patterns of TOP1-mediated neuronal genomic damage shared by major neurodegenerative disorders.

Cell·2026
Same journal

Four-dimensional molecular mapping from a spatial snapshot reveals the dynamics of hair follicle organogenesis.

Cell·2026
Same journal

Whole-cell particle-based digital twin simulations from 4D lattice light-sheet microscopy data.

Cell·2026
See all related articles

Related Experiment Video

Updated: May 3, 2026

Lipid Exchange Assay in Living Cells
08:59

Lipid Exchange Assay in Living Cells

Published on: March 21, 2025

1.2K

The changing lipidome during cell division.

Arnaud Echard1, David Burgess2

  • 1Membrane Traffic and Cell Division Lab, Institut Pasteur and CNRS URA2582, 25-28 rue du Dr. Roux, 75015 Paris, France.

Cell
|February 4, 2014
PubMed
Summary
This summary is machine-generated.

Lipids dynamically change during cell division, playing key roles in membrane rearrangements and the completion of cytokinesis, according to new research on lipidome dynamics.

More Related Videos

Author Spotlight: Advancing Cell Membrane Biophysics - Exploring Interactions and Challenges Through Experimental and Computational Approaches
07:31

Author Spotlight: Advancing Cell Membrane Biophysics - Exploring Interactions and Challenges Through Experimental and Computational Approaches

Published on: September 1, 2023

3.3K
Analysis of Lipid Droplet Content in Fission and Budding Yeasts using Automated Image Processing
08:43

Analysis of Lipid Droplet Content in Fission and Budding Yeasts using Automated Image Processing

Published on: July 17, 2019

7.4K

Related Experiment Videos

Last Updated: May 3, 2026

Lipid Exchange Assay in Living Cells
08:59

Lipid Exchange Assay in Living Cells

Published on: March 21, 2025

1.2K
Author Spotlight: Advancing Cell Membrane Biophysics - Exploring Interactions and Challenges Through Experimental and Computational Approaches
07:31

Author Spotlight: Advancing Cell Membrane Biophysics - Exploring Interactions and Challenges Through Experimental and Computational Approaches

Published on: September 1, 2023

3.3K
Analysis of Lipid Droplet Content in Fission and Budding Yeasts using Automated Image Processing
08:43

Analysis of Lipid Droplet Content in Fission and Budding Yeasts using Automated Image Processing

Published on: July 17, 2019

7.4K

Area of Science:

  • Cell Biology
  • Biochemistry

Background:

  • Cell division involves significant membrane remodeling.
  • The precise roles of lipids in these dynamic processes remain incompletely understood.

Purpose of the Study:

  • To investigate the lipidome dynamics throughout cell division.
  • To elucidate the specific functions of lipids during cytokinesis.

Main Methods:

  • Quantitative analysis of lipid composition changes.
  • Cellular imaging techniques to observe lipid localization.

Main Results:

  • Significant alterations in lipid profiles were observed during cell division.
  • Specific lipids were identified as crucial for membrane scission and cell separation.

Conclusions:

  • Lipid dynamics are integral to successful cell division.
  • Targeting specific lipids may offer new avenues for controlling cell division processes.