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Tumor Immunotherapy

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.

Cancer Therapies

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...

Cancer Vaccines

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...

Targeted Cancer Therapies

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...

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Related Experiment Video

Updated: May 3, 2026

A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies

A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies

Published on: March 12, 2014

Immunotherapy for solid tumors--a review for surgeons.

Abdul Saied¹, Venu G Pillarisetty², Steven C Katz³

¹Department of Surgery, Roger Williams Medical Center, Providence, Rhode Island.

The Journal of Surgical Research

|February 4, 2014

Summary

This summary is machine-generated.

Immunotherapy is now key for advanced solid tumors. This review explains immunotherapy principles, mechanisms, clinical data, and its integration into cancer care for clinicians and surgeons.

Keywords:

Adoptive cell transfer therapy Immunotherapy Solid tumors

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Area of Science:

Oncology
Immunology
Surgical Oncology

Background:

Immunotherapy has significantly advanced in the past decade.
It is now a crucial treatment for advanced solid tumors.
Understanding immunotherapy is vital for clinicians, particularly surgeons.

Purpose of the Study:

To review the evolution of key immunotherapies.
To explain their mechanisms of action and clinical supporting data.
To guide the integration of immunotherapy into multidisciplinary cancer management.

Main Methods:

Literature review of relevant immunotherapies.
Summary of mechanisms of action.
Analysis of clinical data and integration strategies.

Main Results:

Immunotherapy has evolved substantially, offering new treatment options.
Established clinical data supports its use in various advanced solid tumors.
Multidisciplinary integration is essential for optimal patient outcomes.

Conclusions:

Immunotherapy is an integral part of advanced solid tumor treatment.
Clinicians and surgeons require foundational knowledge of immunotherapy.
This review serves as a primer for understanding this rapidly evolving field.