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Updated: May 3, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
Occipital and craniocervical pain and brain MRI in children with migraine
Tal Eidlitz-Markus1, Avraham Zeharia1, Yishai Haimi-Cohen1
1Pediatric Headache Clinic, Ambulatory Day Care Hospitalization Unit, Schneider Children's Medical Center of Israel, Petach Tikva, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Insights
Pediatric migraine patients may experience cervical and occipital pain, but these symptoms are not unique to migraine. Conventional brain MRI scans show no specific anatomical changes linked to this pain in children and adolescents.
Area of Science:
- Pediatric Neurology
- Neuroimaging
- Pain Management
Background:
- Cervical and occipital pain are reported in pediatric migraine patients.
- Conventional brain MRI has not identified anatomical changes explaining this pain in children.
- The pathophysiology of headache with cervical and occipital pain in pediatric patients remains unclear.
Purpose of the Study:
- To determine the frequency of cervical and occipital pain in pediatric patients with migraine compared to other headache types.
- To investigate if conventional brain MRI reveals corresponding anatomical abnormalities in children and adolescents with headache.
Main Methods:
- Retrospective review of 194 pediatric patients with headache.
- Analysis of medical files and conventional brain magnetic resonance imaging (MRI) scans.
- Patients categorized into migraine headache (n=125) and other headache types (n=69).
Main Results:
- Occipital pain was reported by 16.4% and cervical pain by 4.1% of patients.
- Neither occipital nor cervical pain was found to be characteristic of migraine headache.
- Conventional brain MRI showed no anatomic changes specific to any headache group, irrespective of pain location.
Conclusions:
- Occipital and cervical pain are not distinguishing symptoms for any headache group in pediatric patients.
- The presence or absence of occipital and cervical pain does not correlate with findings on conventional brain MRI in children and adolescents.
- Further research may be needed to understand the underlying mechanisms of these pain types in pediatric headaches.
Background:
Both cervical and occipital pain has been reported in pediatric patients with migraine. There are no descriptions of anatomical changes on conventional brain magnetic resonance imaging that can explain the pathophysiology of headache with cervical and occipital pain in this age group. Our aim was to evaluate the frequency of cervical and occipital pain in children and adolescents with migraine as opposed to other types of headache and to seek corresponding anatomic abnormalities on brain magnetic resonance imaging.
Methods:
The cohort included 194 patients with headache attending the ambulatory headache clinic of a pediatric tertiary medical center. Data were collected by medical file review and revision of conventional magnetic resonance scans.
Results:
Patients were divided into two groups: migraine headache (n = 125) and other types of headache (n = 69). Occipital pain was reported by 16.4% of the patients and cervical pain by 4.1%; neither type of pain was characteristic of migraine headache in particular. Brain magnetic resonance imaging did not show any anatomic changes specific to migraine or other headache types, regardless of the presence of occipital or cervical pain.
Conclusions:
Occipital and cervical pain are not characteristic symptoms of any headache group in the pediatric age group, and their presence or absence does not correspond to changes on conventional brain magnetic resonance imaging.
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