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Expression of functional potassium channels from Shaker cDNA in Xenopus oocytes
L C Timpe1, T L Schwarz, B L Tempel
1Howard Hughes Medical Institute, University of California, San Francisco 94143.
Nature
|January 14, 1988
Abstract:
The Shaker gene of Drosophila melanogaster encodes a potassium-selective ion channel, the 'A' channel, or one of its subunits. A single Shaker messenger RNA species suffices to direct the synthesis of functional A channels in Xenopus oocytes. Physiological characteristics of the A currents induced by two different mRNA species are compared.