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Author Spotlight: Recent Advancements in Reoperative Foregut Surgery
Published on: September 22, 2023
The effects of transoral incisionless fundoplication on chronic GERD patients: 12-month prospective multicenter
Erik B Wilson1, William E Barnes, Peter G Mavrelis
1*Department of Surgery, The University of Texas Health Science Center, Houston ¶Master Center for Minimally Invasive Surgery, Southlake #Ihde Surgical Group, Arlington, TX †Livingston Hospital and Healthcare Services Inc., CAH, Salem, KY ‡Internal Medicine Associates, Merrillville, IN §Mt Graham Regional Medical Center, Safford ##Tempe St Luke's Hospital, Tempe, AZ ∥SurgOne Foregut Institute, Englewood, CO **Allegan Surgical Associates, Allegan, MI ††Munroe Regional Medical Center, Ocala, FL ‡‡Utah County Surgical Associates, Orem, UT §§Crossville Medical Group, PA, Crossville, TN ∥∥Department of Surgery, The George Washington University School of Medicine & Health Sciences, Washington, DC ¶¶Reston Surgical Associates, Reston, VA ***The Surgeons Group of Baton Rouge, Baton Rouge, LA †††EndoGastric Solutions Inc., Redmond, WA.
Purpose:
This study aimed to assess the impact of transoral incisionless fundoplication (TIF) on patients with chronic gastroesophageal reflux disease (GERD) at 12-month follow-up.
Methods:
Clinical outcomes of 100 consecutive patients with chronic GERD who underwent TIF between January 2010 and February 2011 were analyzed.
Results:
There were no major complications reported. Esophageal acid exposure was normalized in 14/27 (52%) of patients who underwent 12-month pH testing. Seventy-four percent of all patients were off proton pump inhibitors versus 92% on daily proton pump inhibitors before TIF, P<0.001. Daily bothersome heartburn and regurgitation symptoms were eliminated in 66/85 (78%) and 48/58 (83%) of patients. Median reflux symptom index score was reduced from 20 (0 to 41) to 5 (0 to 44), P<0.001. Two patients reported de novo dysphagia and 1 patient reported bloating (scores 0 to 3). Six patients underwent revision; 5 laparoscopic Nissen fundoplication and 1 TIF.
Conclusions:
TIF provided a safe and effective therapeutic option for carefully selected patients with chronic GERD.
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