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Lithium intoxication presenting as a mixed misidentification syndrome.

S G Potts1

  • 1Maudsley Hospital, Denmark Hill, Camberwell, London SE5 8AZ, UK.

Behavioural Neurology
|February 4, 2014
PubMed
Summary

Lithium intoxication can cause Capgras syndrome, a misidentification disorder. Right hemisphere brain damage may increase the risk of these neurological symptoms.

Area of Science:

  • Neurology
  • Toxicology
  • Psychiatry

Background:

  • Lithium is a common mood stabilizer.
  • Misidentification syndromes are rare neurological conditions.
  • Capgras syndrome involves the delusion that familiar people are impostors.

Purpose of the Study:

  • To report a case of lithium intoxication presenting with Capgras syndrome.
  • To explore the association between right hemisphere lesions and misidentification syndromes.

Main Methods:

  • Case report of a patient with lithium intoxication.
  • Computed Tomography (CT) scan of the brain.

Main Results:

  • The patient presented with a mixed misidentification syndrome, including Capgras syndrome features.

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  • CT scan revealed cerebral atrophy, more pronounced on the right side.
  • Findings support the hypothesis linking right hemisphere lesions to misidentification syndromes.

    • Conclusions:

    • Lithium intoxication can precipitate complex neuropsychiatric symptoms.
    • Right-sided cerebral atrophy may predispose individuals to misidentification syndromes like Capgras.
    • This case highlights the importance of considering medication toxicity in neurological presentations.