Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Long-term Depression01:05

Long-term Depression

27.3K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
27.3K
Long-term Depression01:03

Long-term Depression

2.6K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over...
2.6K
Transient Ischemic Attack l: Introduction01:26

Transient Ischemic Attack l: Introduction

18
A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...
18

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reply to: "1.5 Dissociation" of somatoparaphrenia for the upper limb and neglect for the lower limb following a thalamic stroke presenting as flaccid hemiparesis: rehabilitation applications and neuroscience implications.

Experimental brain research·2019
Same author

New ischaemic brain lesions in cervical artery dissection stratified to antiplatelets or anticoagulants.

European journal of neurology·2015
Same author

Illusory Reduplication of One's Own Body: Phenomenology and Classification of Autoscopic Phenomena.

Cognitive neuropsychiatry·2014
Same author

Dementia reversible by plasmapheresis in multiple myeloma.

Behavioural neurology·2014
Same author

Anterograde and retrograde amnesia following bitemporal infarction.

Behavioural neurology·2014
Same author

Ideomotor Apraxia in Left Thalamic Hemorrhage: Discrepancy between Clinical Course and SPECT.

Behavioural neurology·2014

Related Experiment Video

Updated: May 3, 2026

Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method
07:12

Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method

Published on: August 2, 2021

3.5K

Relapsing depression in paramedian thalamic infarctions.

R W Baumgartner1, T Landis1, M Regard1

  • 1Department of Neurology, University Hospital, Zürich, Switzerland.

Behavioural Neurology
|February 4, 2014
PubMed
Summary

Acute depression episodes in a patient were linked to relapsing paramedian thalamic infarctions. These brain lesions may explain the transient depressive symptoms and associated neurological deficits.

Keywords:
DepressionInfarctionStrokeThalamus

More Related Videos

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder
08:20

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder

Published on: August 11, 2015

13.0K
Circumscribed Capsular Infarct Modeling Using a Photothrombotic Technique
08:25

Circumscribed Capsular Infarct Modeling Using a Photothrombotic Technique

Published on: June 2, 2016

7.3K

Related Experiment Videos

Last Updated: May 3, 2026

Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method
07:12

Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method

Published on: August 2, 2021

3.5K
MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder
08:20

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder

Published on: August 11, 2015

13.0K
Circumscribed Capsular Infarct Modeling Using a Photothrombotic Technique
08:25

Circumscribed Capsular Infarct Modeling Using a Photothrombotic Technique

Published on: June 2, 2016

7.3K

Area of Science:

  • Neurology
  • Neuropsychiatry

Background:

  • Depression is increasingly linked to central nervous system (CNS) lesions.
  • Cerebral hemisphere infarctions are commonly associated with depression.
  • The role of specific brain regions, like the thalamus, in depression requires further investigation.

Purpose of the Study:

  • To report a case study linking relapsing paramedian thalamic infarctions to episodes of acute depression.
  • To explore the potential causal relationship between thalamic lesions and depressive symptoms.

Main Methods:

  • Case report detailing a patient with recurrent depression.
  • Clinical observation of neurological and neuropsychological deficits.
  • Neuroimaging to identify brain lesions, specifically in the thalamus.

Main Results:

  • The patient experienced two distinct episodes of acute depression.
  • Both depression episodes correlated with relapsing paramedian thalamic infarctions.
  • Associated symptoms included transient neuropsychological deficits, hypersomnia, and left facial sensory disturbance.

Conclusions:

  • Paramedian thalamic infarctions can manifest with diverse neurological and psychiatric symptoms.
  • Thalamic lesions, similar to hemispheric strokes, may cause higher functional deficits.
  • The study suggests paramedian thalamic infarctions may be responsible for transient depression in this patient.