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Thyroid nodules ≥ 4 cm: can ultrasound and cytology reliably exclude cancer? Reply

Linwah Yip1

  • 1Department of Surgery, School of Medicine, University of Pittsburgh, Suite 101-3471 Fifth Avenue, Pittsburgh, PA, 15213, USA, yipl@upmc.edu.

World Journal of Surgery
|February 4, 2014
PubMed
Abstract

No abstract available in PubMed .

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Goiter refers to an abnormal enlargement of the thyroid gland that may appear as a diffuse goiter (uniform enlargement) or nodular (single or multiple nodules). Functionally, it is classified as nontoxic (normal/low hormone levels) or toxic (excess hormone production).PathophysiologyDiffuse thyroid enlargement typically results from prolonged stimulation by thyroid-stimulating hormone (TSH) or TSH-like agents, commonly seen in hypothyroidism or iodine deficiency. In contrast, in hyperthyroid...
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