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If a reaction has a small equilibrium constant, the equilibrium position favors the reactants. In such reactions, a negligible change in concentration may occur if the initial concentrations of reactants are high and the Kc value is small. In such circumstances, the equilibrium concentration is approximately equal to its initial concentration. This estimation can be used to simplify the equilibrium calculations by assuming that some equilibrium concentrations are equal to the initial...
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Big strokes for little folks

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  • 1From the Departments of Neurosciences and Pediatrics (D.A.T.), University of California, San Diego, La Jolla; Rady Children's Hospital (D.A.T.), San Diego, CA; The Ohio State University College of Medicine (W.L.), Columbus; and Nationwide Children's Hospital (W.L.), Columbus, OH.

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