Factors affecting cognitive outcome in early pediatric stroke

Martina Studer1, Eugen Boltshauser, Andrea Capone Mori

  • 1From University Children's Hospital Berne (M. Studer, E.W., T.H., M. Steinlin); Center for Cognition, Learning and Memory (M. Studer, T.H., M. Steinlin), University of Berne; University Children's Hospital Zürich (E.B., A.H.); Children's Hospital Aarau (A.C.M.); University Children's Hospital Basel (A.D.); University Children's Hospital Geneva (J.F.); Children's Hospital Neuchâtel (D.M.); Children's Hospital Chur (E.K.); Children's Hospital St. Gallen (O.M.); Children's Hospital Sion (J.-P.M.); Children's Hospital Bellinzona (G.-P.R.); University Children's Hospital Lausanne (C.P.); Children's Hospital Winterthur (R.S.); and Children's Hospital Lucerne (T.S.-M.), Switzerland.

Neurology
|February 4, 2014
PubMed
Summary

Children with arterial ischemic stroke (AIS) often have lower cognitive performance, especially in memory and processing speed. Young age at stroke, seizures, and lesion location are risk factors for poorer cognitive outcomes.

Related Concept Videos

Ischemic Stroke ll: Pathophysiology01:15

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
54
Information Processing Approach01:30

Information Processing Approach

The information-processing theory of cognitive development centers on fundamental mental processes, including attention, memory, and problem-solving skills. Researchers in this field examine how cognitive abilities, such as working memory, evolve and influence children's overall development. Studies indicate that children with stronger working memory tend to excel in reading comprehension, math, and problem-solving compared to peers with less efficient memory skills. Low working memory is...
889
Ischemic Stroke l: Introduction01:15

Ischemic Stroke l: Introduction

Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
44
Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
30