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Related Concept Videos

Clinical Trials01:16

Clinical Trials

8.5K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
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Statistical Software for Data Analysis and Clinical Trials01:12

Statistical Software for Data Analysis and Clinical Trials

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Statistical software is pivotal in data analysis and clinical trials by providing tools to analyze data, draw conclusions, and make predictions. These software packages range from simple data management applications to complex analytical platforms, supporting various statistical tests, models, and simulation techniques. Their significance lies in their ability to handle vast amounts of data with precision and efficiency, enabling researchers to validate hypotheses, identify trends, and make...
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Clinical Trials: Overview01:11

Clinical Trials: Overview

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Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
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Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

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Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
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Issues And Trends In Healthcare Delivery System01:29

Issues And Trends In Healthcare Delivery System

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The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
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Purpose of Health Records II01:19

Purpose of Health Records II

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Health records serve various essential purposes in the healthcare system. Here are some key purposes:
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Related Experiment Video

Updated: May 3, 2026

Databases to Efficiently Manage Medium Sized, Low Velocity, Multidimensional Data in Tissue Engineering
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Use of databases for clinical research.

Yoon K Loke

    Archives of Disease in Childhood
    |February 4, 2014
    PubMed
    Summary

    Electronic patient databases offer valuable research insights for disease causes and outcomes when clinical trials are not feasible. Careful data selection and validation are crucial for reliable results.

    Area of Science:

    • Health Informatics
    • Clinical Research Methodology
    • Epidemiology

    Background:

    • Electronic databases capture patient data across clinical and administrative settings.
    • While randomized controlled trials (RCTs) are the gold standard, databases offer alternative research avenues.
    • Databases often originate from administrative or financial purposes, necessitating careful consideration for research use.

    Purpose of the Study:

    • To highlight the value of electronic patient databases in clinical research.
    • To discuss the considerations and challenges in utilizing database research.
    • To explore the potential of hybrid models combining randomization with database efficiency.

    Main Methods:

    • The abstract discusses the nature and application of electronic databases in research.
    Keywords:
    Evidence Based MedicineHealth ServiceInformation TechnologyOutcomes Research

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  • It emphasizes the importance of data accuracy and diagnostic validation.
  • It reviews the advantages of using existing databases for outcome data collection.

    • Main Results:

    • Databases provide valuable data for etiological and prognostic studies, especially when RCTs are impractical.
    • High-quality databases facilitate outcome data capture from routine care, reducing follow-up burdens.
    • Hybrid models integrating randomization with database efficiency show promise.

    Conclusions:

    • Electronic databases are essential tools for specific research questions, complementing RCTs.
    • Strategic planning, including data set identification and validation, is critical for successful database research.
    • Future research can leverage hybrid approaches for efficient and robust clinical studies.