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Bacterial entropathogens and antimicrobial susceptibility in children with acute diarrhea in Babol, Iran

Mohammad Reza Esmaeili Dooki1, Ramazan Rajabnia2, Rahim Barari Sawadkohi2

  • 1Non-Communicable pediatric Diseases Research Center, Babol University of Medical Sciences, Babol, Iran.

Caspian Journal of Internal Medicine
|February 4, 2014
PubMed

Insights

Escherichia coli (E.coli) and Shigella were the most common bacterial causes of infectious diarrhea in children in Iran. Ceftizoxime is effective against Shigella, but Cefixime is not recommended.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Microbiology

Background:

  • Infectious diarrhea is a significant global cause of child mortality and morbidity.
  • Identifying common bacterial pathogens and their antibiotic resistance is crucial for effective treatment.

Purpose of the Study:

  • To identify prevalent bacteria causing diarrhea in children.
  • To determine the antimicrobial susceptibility patterns of these bacteria.

Main Methods:

  • Bacterial culture and isolation from fecal specimens of children under 14 with acute diarrhea.
  • Antimicrobial susceptibility testing using disk diffusion and micro dilution methods.

Main Results:

  • Bacteria were isolated in 27.9% of 172 pediatric patients.
  • E.coli and Shigella were the most frequently identified pathogens.
  • Shigella isolates were susceptible to Ceftizoxime and ciprofloxacin but resistant to Cefixime.

Conclusions:

  • E.coli is the leading bacterial cause of childhood diarrhea in the studied region.
  • Ceftizoxime is a suitable antibiotic for treating childhood shigellosis, while Cefixime is not recommended.
Abstract

Keywords:
AntibioticDiarrheaDrugDysentery.Resistance

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