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Modified Radical Neck Dissection for Cervical Metastasis
Published on: February 20, 2026
231
Harmonic scalpel versus conventional haemostasis in neck dissection: a prospective randomized study
Emanuele Ferri1, Enrico Armato2, Giacomo Spinato3
1Otorhinolaryngology Department ULSS 17, General Hospital of Monselice, Via G. Marconi 19, Monselice, 35043 Padua, Italy.
International Journal of Surgical Oncology
|February 4, 2014
Summary
The harmonic scalpel (HS) significantly reduces operative time, blood loss, and pain during neck dissection (ND) for head and neck cancer. This study found HS to be a safe and effective alternative to conventional hemostasis.
Area of Science:
- Surgical Oncology
- Head and Neck Surgery
- Minimally Invasive Techniques
Background:
- Neck dissection (ND) is a critical procedure for head and neck squamous cell carcinoma (HNSCC).
- Optimizing operative factors and patient outcomes in ND remains a key focus in surgical practice.
Purpose of the Study:
- To compare the harmonic scalpel (HS) with conventional hemostasis (CH) in terms of operative factors, postoperative outcomes, and complications during ND for HNSCC.
- To evaluate the efficacy and safety of HS in reducing surgical morbidity.
Main Methods:
- Prospective randomized trial involving 61 patients with primary HNSCC undergoing ND.
- Patients were randomized into two groups: conventional hemostasis (CH) and harmonic scalpel (HS).
- Key outcomes measured included operative time, blood loss, drainage volume, pain, hospital stay, and complication rates.
Main Results:
- The HS group demonstrated significantly reduced operative time, intraoperative blood loss, postoperative pain, and drainage volume compared to the CH group.
- No significant differences were found in mean hospital stay or the incidence of perioperative and postoperative complications between the two groups.
Conclusions:
- The harmonic scalpel (HS) is a reliable and safe tool for neck dissection (ND) in HNSCC patients.
- HS effectively reduces intraoperative blood loss, operative time, drainage volume, and postoperative pain.
- Further multicenter randomized studies are warranted to confirm these advantages and assess the cost-benefit ratio.

