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Core/shell nanoparticles in biomedical applications.

Krishnendu Chatterjee1, Sreerupa Sarkar1, K Jagajjanani Rao1

  • 1Interfaces and Nanomaterials Laboratory, Department of Chemical Engineering, National Institute of Technology, Rourkela 769008, Orissa, India.

Advances in Colloid and Interface Science
|February 5, 2014
PubMed
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Core/shell nanoparticles show great promise for biomedical applications like bioimaging and drug delivery. This review covers their development and diverse uses over the last two decades.

Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Nanotechnology

Background:

  • Nanoparticles offer significant advantages in various fields, particularly in biomedicine.
  • Core/shell nanoparticles present superior properties compared to simple nanoparticles for biomedical applications.

Purpose of the Study:

  • To review the advancements in core/shell nanoparticle-based biomedical research over the past two decades.
  • To categorize the applications of different core/shell nanoparticle types.

Main Methods:

  • Literature review of core/shell nanoparticle research.
  • Classification of applications based on key biomedical areas.

Main Results:

  • Core/shell nanoparticles have demonstrated significant potential in bioimaging, biosensing, and targeted drug/gene delivery.
Keywords:
BioimagingBiomedicalCore/shell nanoparticlesDrug deliveryMRI

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  • Their unique structure provides enhanced performance for various biomedical tasks.
  • Applications span targeted drug delivery, DNA/RNA interaction studies, and gene therapy.
  • Conclusions:

    • Core/shell nanoparticles are a highly promising class of nanomaterials for advanced biomedical applications.
    • Continued research is expected to further expand their utility in medicine and diagnostics.