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Related Experiment Video

Updated: Jan 25, 2026

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss

Published on: April 11, 2025

Theoretical frameworks for multiscale modeling and simulation.

Huan-Xiang Zhou¹

¹Department of Physics and Institute of Molecular Biophysics, Florida State University, Tallahassee, FL 32306, USA.

Current Opinion in Structural Biology

|February 5, 2014

Summary

This summary is machine-generated.

Modeling biomolecular systems across scales, from electrons to bulk properties, has advanced significantly. Interfacing between these scales is improving, enabling accurate in vivo biochemical process studies soon.

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Multiscale Structures Aggregated by Imprinted Nanofibers for Functional Surfaces

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Published on: September 11, 2018

Area of Science:

Computational biology
Multiscale modeling
Biophysics

Background:

Biomolecular systems are modeled across diverse scales, from quantum mechanics to continuum mechanics.
Interfacing between these different modeling scales presents significant challenges.

Purpose of the Study:

To review the advancements in multiscale modeling of biomolecular systems.
To highlight the progress in bridging different scales for biochemical process simulation.

Main Methods:

Review of existing multiscale modeling approaches.
Analysis of methods for interfacing models at different resolutions.

Main Results:

Significant progress has been made in overcoming challenges of scale interfacing.
Multiple models at different scales are effectively used for studying systems and properties like channel conductance.

Conclusions:

Accurate modeling of biochemical processes under in vivo conditions is becoming achievable.
Bridging molecular and subcellular scales in biomolecular modeling is nearing reality.