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Prevalence and patterns of demyelinating central nervous system disorders in urban Mangalore, South India

Lekha Pandit1, Rashmi Kundapur2

  • 1KS Hegde Medical Academy, Nitte University, Mangalore, India panditmng@gmail.com.

Multiple Sclerosis (Houndmills, Basingstoke, England)
|February 5, 2014
PubMed

Insights

This study provides initial epidemiological data on multiple sclerosis (MS) and related demyelinating disorders in India, revealing a crude prevalence of 8.3/100,000 for MS. Further research is needed to determine the true prevalence of these neurological conditions.

Area of Science:

  • Neurology
  • Epidemiology

Background:

  • Limited epidemiological data exists for multiple sclerosis (MS) and related demyelinating disorders in India.
  • Understanding the prevalence of these conditions is crucial for public health planning and resource allocation.

Purpose of the Study:

  • To estimate the prevalence of multiple sclerosis (MS), clinically-isolated syndrome (CIS), and Neuromyelitis Optica Spectrum Disorders (NMOSD) in India.
  • To establish a baseline for future epidemiological studies on demyelinating disorders in the region.

Main Methods:

  • A registry-based method was employed to collect data from secure sources.
  • Index cases were verified, and a total of 79 patients with demyelinating disorders were identified.

Main Results:

  • The crude prevalence for MS was found to be 8.3/100,000, and for CIS, it was 6.2/100,000.
  • Age-standardized prevalence of MS relative to the world population was 7.8/100,000.
  • Neuromyelitis Optica (NMO) and spectrum disorders (NMOS) accounted for 13.9% of all demyelinating disorders, with a prevalence of 2.6/100,000.

Conclusions:

  • This study provides the first epidemiological estimates for MS and related disorders in India.
  • Larger studies utilizing more refined survey methodologies are necessary to ascertain the precise prevalence of demyelinating disorders across India.
Keywords:
Clinically isolated syndromeIndiademyelinating disordersepidemiologymultiple sclerosisneuromyelitis opticaprevalenceregistry

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