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Hypoactive medial prefrontal cortex functioning in adults reporting childhood emotional maltreatment

Anne-Laura van Harmelen1, Marie-José van Tol2, Tim Dalgleish3

  • 1Leiden Institute for Brain and Cognition (LIBC), Postzone C2-S, P.O. Box 9600, 2300 RC Leiden, the Netherlands, Clinical, Health and Neuropsychology Unit, Leiden University, Pieter de la Court Gebouw, Wassenaarseweg 52, 2333 AK Leiden, the Netherlands, Department of Developmental Psychiatry, University of Cambridge School of Clinical Medicine, Box 189 Cambridge Biomedical Campus, Cambridge, UK, CB2 2QQ, Department of Psychiatry, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, the Netherlands, Neuro-imaging Center, University Medical Center Groningen, and Department of Psychology, University of Groningen, Antonius Deusinglaan 29713 AW Groningen, the Netherlands, Medical Research Council, Cognition and Brain Sciences Unit, 15 Chaucer Road, Cambridge, UK CB2 7EF, and Department of Psychiatry, VU University Medical Center, A.J. Ernststraat 1187, 1081 HL Amsterdam, the Netherlands Leiden Institute for Brain and Cognition (LIBC), Postzone C2-S, P.O. Box 9600, 2300 RC Leiden, the Netherlands, Clinical, Health and Neuropsychology Unit, Leiden University, Pieter de la Court Gebouw, Wassenaarseweg 52, 2333 AK Leiden, the Netherlands, Department of Developmental Psychiatry, University of Cambridge School of Clinical Medicine, Box 189 Cambridge Biomedical Campus, Cambridge, UK, CB2 2QQ, Department of Psychiatry, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, the Netherlands, Neuro-imaging Center, University Medical Center Groningen, and Department of Psychology, University of Groningen, Antonius Deusinglaan 29713 AW Groningen, the Netherlands, Medical Research Council, Cognition and Brain Sciences Unit, 15 Chaucer Road, Cambridge, UK CB2 7EF, and Department of Psychiatry, VU University Medical Center, A.J. Ernststraat 1187, 1081 HL Amsterdam, the Netherlands Leiden Institute for Brain and Cognition (LIBC), Postzone C2-S, P.O. Box 9600, 2300 RC Leiden, the Netherlands, Clinical, Health and Neuropsychology Unit, Leiden University, Pieter de la

Social Cognitive and Affective Neuroscience
|February 5, 2014
PubMed
Abstract

Keywords:
Anxietychildhood abusedepressionemotional maltreatmentmagnetic resonance imaging (MRI)medial prefrontal cortex (PFC)

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