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Updated: May 3, 2026

Mass Spectrometry and Luminogenic-based Approaches to Characterize Phase I Metabolic Competency of In Vitro Cell Cultures
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Possible involvement of nuclear factor erythroid 2-related factor 2 in the gene expression of Cyp2b10 and Cyp2a5

Takashi Ashino1, Haruyo Ohkubo-Morita1, Masayuki Yamamoto2

  • 1Division of Toxicology, Department of Pharmacology, Toxicology and Therapeutics, Showa University School of Pharmacy, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan.

Redox Biology
|February 5, 2014
PubMed

Keywords:
ARE, antioxidant response elementCAR, constitutive androstane receptorCyp2a5Cyp2b10Gapdh, glyceraldehyde-3-phosphate dehydrogenaseHmox1, heme oxygenase-1Maf, musculoaponeurotic fibrosarcoma oncogene homologMouseNqo1, NAD(P)H-quinone oxidoreductase-1Nrf2, nuclear-factor erythroid 2-related factor 2Nuclear-factor erythroid 2-related factor 2P450, cytochrome P450PBREM, phenobarbital responsive element modulePCR, polymerase chain reactionPhenobarbitalPhorone

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