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Updated: May 3, 2026

Technical Aspects of the Mouse Aortocaval Fistula
Published on: July 11, 2013
Fistula eligibility: a work in progress
Ahmed A Al-Jaishi1, Louise M Moist
1Kidney Clinical Research Unit, London Health Sciences Centre, London, Ontario, Canada; Kidney, Dialysis, Transplantation Program, Institute for Clinical Evaluative Sciences (ICES-KDT), London, Ontario, Canada.
Insights
Choosing the right hemodialysis vascular access is crucial. While fistulas are preferred, their eligibility isn't always clear, necessitating careful patient assessment for optimal outcomes.
Area of Science:
- Nephrology
- Vascular Surgery
- Radiology
Background:
- Effective hemodialysis relies on appropriate vascular access.
- Clinical guidelines favor arteriovenous fistulas (AVF) over grafts and catheters.
- Growing concerns exist regarding fistula primary failure rates and patient suitability.
Purpose of the Study:
- To review initiatives addressing patient suitability for arteriovenous access.
- To define criteria for fistula eligibility in hemodialysis patients.
- To explore factors influencing fistula creation and use.
Main Methods:
- Discussion of process of care improvements for AV access.
- Review of radiological and non-radiological diagnostic tests for access assessment.
- Examination of alternative surgical approaches for vascular access.
Main Results:
- Several initiatives have improved patient suitability assessment for AV access.
- Defined criteria for fistula eligibility remain unvalidated.
- Integration of patient, biological, and surgical factors is complex for fistula planning.
Conclusions:
- Optimizing hemodialysis vascular access requires careful clinical judgment and individualized assessment.
- Appropriate vascular access selection minimizes prolonged catheter dependence.
- A comprehensive approach to risk-benefit analysis improves patient outcomes.
Abstract:
Effective hemodialysis requires a reliable vascular access. Clinical practice guidelines strongly recommend the fistula as the preferred option followed by arteriovenous (AV) grafts, with central venous catheters being least preferred. Recently, there has been a growing awareness of the limitations of the fistula, its high rate of primary failure and that a fistula may not be appropriate for all patients initiating or on hemodialysis. However, determinates for fistula eligibility have not been clearly defined. The creation and use of a fistula requires the complex integration of patient, biological, and surgical factors, none of which can be easily predicted or planned. There have been several successful initiatives over the last decade addressing patient suitability for AV access, but none have validated defined criteria for fistula eligibility. We discuss these initiatives by addressing: 1) process of care, 2) radiological and nonradiological tests and procedures, and 3) alternative surgical approaches. Careful clinical judgment, appropriate vascular access assessment and placement, and an individualized approach to the risks and benefits will optimize patient health outcomes while minimizing prolonged catheter dependence among hemodialysis patients.

