Related Experiment Video
Updated: May 3, 2026

A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
Temperament, hopelessness, and attempted suicide: direct and indirect effects
Anthony J Rosellini1, Courtney L Bagge
1Department of Psychiatry and Human Behavior, University of Mississippi Medical Center, Jackson, MS, USA; Center for Anxiety and Related Disorders, Boston University, Boston, MA, USA; University of Mississippi Medical Center, Boston University, USA.
Abstract:
This study evaluated whether hopelessness mediated the relations between temperament and recent suicide attempter status in a psychiatric sample. Negative temperament and positive temperament (particularly the positive emotionality subscale) uniquely predicted levels of hopelessness. Although these temperament constructs also demonstrated significant indirect effects on recent suicide attempter status, the effects were partially (for the broad temperament scales) or fully (for the positive emotionality subscale) mediated by the levels of hopelessness. These findings indicate that a tendency to experience excessive negative emotions as well as a paucity of positive emotions may lead individuals to experience hopelessness. Although temperament may also indirectly influence suicide attempter status, hopelessness mediates these relations.
Related Concept Videos
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Avoidance Learning and Learned Helplessness
Avoidance learning occurs when an organism learns that a specific behavior can prevent an unpleasant outcome. For example, a student who receives a bad grade may start studying harder to avoid future poor grades. This behavior persists even when the negative outcome is no longer present. Avoidance learning is powerful because it maintains behavior in the absence of the...
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Benefits of Self-Esteem
Psychological and Sociocultural Causes of Schizophrenia
Impact of Individuals on Individuals

