Related Experiment Video
Updated: May 3, 2026
Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia
Published on: May 26, 2023
Comparative outcomes of elderly stage I lung cancer patients treated with segmentectomy via video-assisted
Cardinale B Smith1, Minal Kale, Grace Mhango
1*Tisch Cancer Institute, † Department of Medicine, Division of General Internal Medicine, Mount Sinai School of Medicine, NY, New York; ‡ Department of Medicine, Division of Hematology/Oncology, Columbia University, NY, New York; §Department of Epidemiology, Mailman School of Public Health, Columbia University, NY, New York; and Departments of ‖Preventive Medicine and ¶ Medicine, Division of Pulmonary and Critical Care Medicine, Mount Sinai School of Medicine, NY, New York.
Introduction:
Video-assisted thorcacic surgery (VATS) is considered an alternative to open lobectomy for the treatment of non-small-cell lung cancer (NSCLC). Limited data are available, however, regarding the equivalence of open versus VATS segmental resections, particularly among elderly patients.
Methods:
From the Surveillance, Epidemiology, and End Results-Medicare database we identified 577 stage I NSCLC patients aged more than 65 years treated with VATS or open segmentectomy. We used propensity score methods to control for differences in the baseline characteristics of patients treated with VATS versus open segmentectomy. Outcomes included perioperative complications, need for intensive care unit, extended hospital stay, perioperative mortality, and survival.
Results:
Overall, 27% of patients underwent VATS. VATS-treated patients had lower rates of postoperative complications (odds ratio [OR]: 0.55, 95% confidence interval [CI]: 0.37-0.83), intensive care unit admissions (OR: 0.18, 95% CI: 0.12-0.28), and decreased length of stay (OR: 0.41, 95% CI: 0.21-0.81) after adjusting for propensity scores. Postoperative outcomes were not significantly different across groups after adjusting for surgeon characteristics. Overall (hazard ratio: 0.80, 95% CI: 0.60-1.06) and lung cancer-specific (hazard ratio: 0.71, 95% CI: 0.45-1.12) survival was similar across groups.
Conclusions:
VATS segmentectomy can be safely performed among elderly NSCLC patients and is associated with equivalent postoperative and oncologic outcomes.
