MR findings of the osteofibrous dysplasia
Joon-Yong Jung1, Won-Hee Jee1, Sung Hwan Hong2
1Department of Radiology, College of Medicine, The Catholic University of Korea, Seoul 137-701, Korea.
Objective:
The aim of this study was to describe MR findings of osteofibrous dysplasia.
Materials And Methods:
MR images of 24 pathologically proven osteofibrous dysplasia cases were retrospectively analyzed for a signal intensity of the lesion, presence of intralesional fat signal, internal hypointense band, multilocular appearance, cortical expansion, intramedullary extension, cystic area, cortical breakage and extraosseous extension, abnormal signal from the adjacent bone marrow and soft tissue and patterns of contrast enhancement.
Results:
All cases of osteofibrous dysplasia exhibited intermediate signal intensity on T1-weighted images. On T2-weighted images, 20 and 4 cases exhibited heterogeneously intermediate and high signal intensity, respectively. Intralesional fat was identified in 12% of the cases. Internal low-signal bands and multilocular appearance were observed in 91%. Cortical expansion was present in 58%. Intramedullary extension was present in all cases, and an entire intramedullary replacement was observed in 33%. Cortical breakage (n = 3) and extraosseous mass formation (n = 1) were observed in cases with pathologic fractures only. A cystic area was observed in one case. Among 21 cases without a pathologic fracture, abnormal signal intensity in the surrounding bone marrow and adjacent soft tissue was observed in 43% and 48%, respectively. All cases exhibited diffuse contrast enhancement.
Conclusion:
Osteofibrous dysplasia exhibited diverse imaging features ranging from lesions confined to the cortex to more aggressive lesions with complete intramedullary involvement or perilesional marrow edema.
Insights
Osteofibrous dysplasia shows varied MR imaging features, often with intermediate T1 signal and diffuse enhancement. Findings range from cortical lesions to aggressive intramedullary involvement, with specific signs like internal bands and expansion being common.
Area of Science:
- Radiology
- Orthopedic Imaging
- Oncologic Imaging
Background:
- Osteofibrous dysplasia is a rare benign bone tumor.
- Accurate diagnosis relies on characteristic imaging findings.
Purpose of the Study:
- To describe the magnetic resonance (MR) imaging findings of osteofibrous dysplasia.
- To correlate imaging features with pathological findings.
Main Methods:
- Retrospective analysis of MR images from 24 pathologically proven osteofibrous dysplasia cases.
- Evaluation of lesion signal intensity, intralesional fat, internal bands, multilocular appearance, cortical changes, intramedullary extension, cystic areas, and enhancement patterns.
Main Results:
- All cases showed intermediate T1 signal intensity; T2 signal was intermediate to high.
- Internal low-signal bands (91%) and multilocular appearance (91%) were frequent.
- Intramedullary extension occurred in all cases (33% complete replacement); cortical expansion in 58%.
- Abnormal marrow/soft tissue signals and diffuse enhancement were common.
Conclusions:
- Osteofibrous dysplasia presents diverse MR imaging features.
- Imaging findings can range from localized cortical lesions to aggressive intramedullary involvement with perilesional edema.
