Hunger whilst "in utero" programming adult osteoporosis
George M Weisz1, William R Albury2
1Department of Orthopaedics, Sydney Wolper Jewish Hospital, School of Humanities, University of New England, Armidale, NSW, Australia, and School of Humanities (Program in History of Medicine), University of NSW, Sydney, Australia and.
Abstract:
The fetal "programming of adult diseases" has been previously reviewed. The descriptions were comprehensive, dealing with the effects of nutritional deprivation on the development of adult metabolic and cardiovascular diseases. During the past decade, research into this "programming" also expanded to the development of osteoporosis. The present review deals with the imbalance of bone mineral metabolism, "programmed" by maternal/fetal/infantile nutritional deprivation, and is illustrated with a family history from the Budapest Ghetto.
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