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Updated: May 3, 2026

Self-Nanoemulsification of Healthy Oils to Enhance the Solubility of Lipophilic Drugs
Published on: July 27, 2022
Solvent effect on ζ potential at an aqueous/oil interface in surfactant-free emulsion
1Key Laboratory of Green Process and Engineering, Institute of Process Engineering, Chinese Academy of Sciences , Beijing 100190, China.
Abstract:
The present study prepared a size-controllable, uniform, and surfactant-free emulsification to investigate the ζ potential of the solvent effect. The results showed that the ratio of electrophoretic mobility changed with droplet diameter, and the correct factor of the ζ potential was determined. The effect of functional groups on the ζ potential was further studied in the presence of an organic hydrophilic solvent. The study characterized the effects of pH, ionic strength, and ionic type on the ζ potential and indicated that the solvents were able to modulate the local electrochemical environment, thus leading to the redistribution of interface charges.
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