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Gestational diabetes mellitus and sleep-disordered breathing
Michèle Bisson1, Frédéric Sériès, Yves Giguère
1Department of Pediatrics, Centre hospitalier universitaire de Québec, the Research Centre, Institut universitaire de cardiologie et pneumologie de Québec, and the Departments of Medical Biology and Endocrinology, CHU de Québec, Université Laval, Quebec City, and the Sleep Laboratory, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, Canada.
Obstetrics and Gynecology
|February 7, 2014
Summary
Gestational diabetes mellitus (GDM) was not linked to sleep-disordered breathing in pregnant women. However, women with GDM reported increased sleepiness, depression risk, and restless legs syndrome.
Area of Science:
- Obstetrics and Gynecology
- Sleep Medicine
- Endocrinology
Background:
- Gestational diabetes mellitus (GDM) is a common pregnancy complication.
- Sleep-disordered breathing (SDB) can affect maternal and fetal health.
- The relationship between GDM and SDB requires further investigation.
Purpose of the Study:
- To investigate the association between gestational diabetes mellitus (GDM) and sleep-disordered breathing (SDB).
- To compare objective and subjective sleep parameters in pregnant women with and without GDM.
Main Methods:
- A case-control study involving pregnant women with (n=26) and without (n=26) GDM.
- Participants underwent home polysomnography between 24-32 weeks of gestation.
- Questionnaires assessed sleepiness, sleep quality, depression risk, and restless legs syndrome.
Main Results:
- No significant differences in apnea-hypopnea index or other SDB measures between GDM and control groups.
- Women with GDM reported significantly higher sleepiness (P=.05).
- Increased prevalence of depression risk (P<.01) and restless legs syndrome (P=.07) in the GDM group.
Conclusions:
- No association found between GDM and objective sleep-disordered breathing in pregnant women with BMI < 35 and no comorbidities.
- GDM may be associated with increased subjective sleep complaints like sleepiness and restless legs syndrome.
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