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Updated: May 3, 2026

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Palladium-catalysed inter- and intramolecular formation of C-O bonds from allenes
1Institut de Chimie Moléculaire de Reims, UMR 7312, CNRS - Université de Reims Champagne-Ardenne, B.P. 1039, 51687 Reims Cedex 2, France. jacques.muzart@univ-reims.fr.
Abstract:
The Pd-catalysed formation of a C-O bond from allenes mainly occurs via the inter- or intramolecular reaction with a hydroxyl group belonging to an alcohol, a phenol or an acid. A carbonyl or a carbonate entity can also be involved. In most cases, the formation of the C-O bond is one step of a domino reaction leading also to a C-C or C-N bond, or to another C-O bond. Thus, a wide range of products, in particular highly functionalized heterocycles, have been synthesised. Catalytic cycles have been proposed but the mechanisms often remain speculative.
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