Related Experiment Video
Updated: May 3, 2026

Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface
Published on: July 10, 2014
Dentine bonding agents comprising calcium-silicates to support proactive dental care: Origins, development and future
1Department of Restorative Dentistry, Biomaterials Science, Biomimetics and Biophotonics (B3) Research Group, King's College London Dental Institute.
Abstract:
The origin of ion-releasing dentine bonding agents lies in a change in attitude regarding the qualities demanded of a restorative dental material. The objectives of this paper are to review recent studies on novel hybrid adhesives comprising bioactive fillers based on information from original research papers, reviews, and patent literatures. Literature searches of free text and MeSH terms were performed by using MedLine (PubMed), Web of Science, Scopus, Scielo and the Cochrane Library (6th November, 2013). Reference lists of primary research reports and eligible systematic reviews were cross-checked in an attempt to identify additional studies. Experimental methacrylate-based adhesives, either when incorporating calcium/sodium phosphate-phyllosilicates or calcium silicate cements, demonstrated to promote therapeutic/protective effects on the micro-mechanical and ultramorphological properties of resin bonded-dentine interfaces associated with mineral deposition over time. Further randomized control trials are needed in order to confirm these initial results in vivo.
Related Concept Videos
Bonding and Strength of Aggregate
Essential Minerals for Bone Health
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Teeth
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
Tooth Anatomy
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
Hydration of Cement
Sulfate Attack on Concrete
Sulfates from sources like soil, groundwater, or industrial effluents...

