Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Peptic Ulcer Disease IV: Management01:26

Peptic Ulcer Disease IV: Management

807
Medical treatment strategies for peptic ulcers encompass various methods. The primary goal of treatment is to diminish gastric acidity and strengthen mucosal defense mechanisms.
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...
807
Drugs for Peptic Ulcer Disease: Sucralfate as Mucosal Protective Agents01:24

Drugs for Peptic Ulcer Disease: Sucralfate as Mucosal Protective Agents

2.3K
In the intricate landscape of the gastric lumen, excessive acid secretion disrupts the natural defense mechanisms, weakening the mucus-bicarbonate barrier. This vulnerability allows pepsin to infiltrate epithelial cells, digesting mucosal proteins and triggering erosion, leading to ulcer formation.
In this scenario, mucosal protective agents like sucralfate play an essential role. Sucralfate, a complex of sulfated sucrose and aluminum hydroxide, demonstrates its usefulness in acidic conditions,...
2.3K
Drugs for Peptic Ulcer Disease: Prostaglandin Analogs as Mucosal Protective Agents01:20

Drugs for Peptic Ulcer Disease: Prostaglandin Analogs as Mucosal Protective Agents

1.7K
The gastric mucosa produces prostaglandins E2 (PGE2) and prostacyclin (PGI2), crucial in maintaining gastric health. They exert cytoprotective effects, including increasing bicarbonate secretion, releasing protective mucin, reducing gastric acid output, and preventing harmful vasoconstriction. These effects are mediated through various receptors, such as EP1, EP2, EP3, and EP4.
Non-steroidal anti-inflammatory drugs (NSAIDs) can induce peptic ulcers by inhibiting cyclooxygenase, decreasing...
1.7K
Peptic Ulcer Disease V: Surgical Management and Nursing Care01:25

Peptic Ulcer Disease V: Surgical Management and Nursing Care

1.3K
Surgical management and nursing care are crucial in treating Peptic Ulcer Disease (PUD). Here is an organized and enhanced overview of the surgical interventions and the associated nursing care for PUD:
Surgical Interventions for Peptic Ulcer Disease
1.3K
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

434
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
434
Acid Suppressive Drugs for Peptic Ulcer Disease: Proton Pump Inhibitors01:13

Acid Suppressive Drugs for Peptic Ulcer Disease: Proton Pump Inhibitors

1.4K
Peptic ulcers, often induced by H. pylori infections or NSAID usage, arise from disruptions in the delicate balance of gastric acid production. Peptic ulcers stem from heightened gastric acid levels due to H. pylori infections or NSAID use. The protective mucus layer diminishes in the presence of these factors, allowing gastric acid to erode the stomach lining and form ulcers.
Gastric acid, a potent cocktail of hydrogen and chloride ions, is produced in specialized parietal cells within the...
1.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Multi-tract percutaneous nephrolithotomy in the management of staghorn stones].

Urologiia (Moscow, Russia : 1999)·2019
Same author

[Analysis of clinical effectiveness and risk factors for complication of percutaneous nephrolototripsia in patients with a solitary kidney].

Urologiia (Moscow, Russia : 1999)·2018
Same author

[Effectiveness of laparoscopic repair of primary strictures of ureteropelvic junction].

Urologiia (Moscow, Russia : 1999)·2018
Same author

[Role of phytotherapy in the treatment of urolithiasis].

Urologiia (Moscow, Russia : 1999)·2012
Same author

[Urgent andrological care in Moscow: current status and perspectives of the service].

Urologiia (Moscow, Russia : 1999)·2012
Same author

[Postoperative lesions of the gastrointestinal tract--actual problem of modern urology].

Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology·2012
Same journal

[CONGENITAL MALFORMATION: BILIARY ATRESIA].

Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology·2018
Same journal

[ASYMPTOMATIC INTRAHEPATIC CHOLANGIOCARCINOMA].

Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology·2018
Same journal

[HEREDITARY HEMOCHROMATOSIS (clinical observations)].

Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology·2018
Same journal

[STAGING SYSTEMS OF HEPATOCELLULAR CARCINOMA].

Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology·2018
Same journal

[COMPARATIVE EXPERIMENTAL EVALUATION OF THE EFFECTIVENESS OF MODERN PROBIOTICS, PREBIOTICS, SYNBIOTICS AND METABIOTICS FOR CORRECTION OF INTESTINAL MICROBIOCENOSIS IN ANIMALS WITH ANTIBIOTIC-ASSOCIATED DYSBIOSIS].

Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology·2018
Same journal

[METABOLIC CORRECTOR WITH HEPATOPROTECTIVE PROPERTIES RUNIHOL®: FROM SCREENING TO CLINICAL TESTING].

Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology·2018
See all related articles

Related Experiment Video

Updated: May 3, 2026

Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection
05:32

Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection

Published on: September 21, 2015

33.7K

[Antiulcer prevention in urological practice].

S K Iarovoĭ, O A Misiakova, Sh Sh Gurbanov

    Eksperimental'Naia I Klinicheskaia Gastroenterologiia = Experimental & Clinical Gastroenterology
    |February 8, 2014
    PubMed
    Summary
    This summary is machine-generated.

    This review examines stress-induced upper gastrointestinal mucosal diseases, including their causes and prevention. Current drug options exist, but optimal selection remains challenging due to limited data, especially in urology patients.

    More Related Videos

    Vessel-sparing Excision and Primary Anastomosis
    08:09

    Vessel-sparing Excision and Primary Anastomosis

    Published on: January 7, 2019

    11.0K
    Chinese Herbal Retention Enema for the Treatment of Ulcerative Colitis
    06:19

    Chinese Herbal Retention Enema for the Treatment of Ulcerative Colitis

    Published on: May 16, 2025

    2.5K

    Related Experiment Videos

    Last Updated: May 3, 2026

    Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection
    05:32

    Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection

    Published on: September 21, 2015

    33.7K
    Vessel-sparing Excision and Primary Anastomosis
    08:09

    Vessel-sparing Excision and Primary Anastomosis

    Published on: January 7, 2019

    11.0K
    Chinese Herbal Retention Enema for the Treatment of Ulcerative Colitis
    06:19

    Chinese Herbal Retention Enema for the Treatment of Ulcerative Colitis

    Published on: May 16, 2025

    2.5K

    Area of Science:

    • Gastroenterology
    • Pharmacology
    • Epidemiology

    Context:

    • Stress-induced gastrointestinal mucosal diseases are a significant clinical concern.
    • Existing literature on their epidemiology, pathogenesis, and risk factors is extensive but fragmented.
    • Data regarding erosive and ulcerative complications in urology patients is particularly limited and debated.

    Purpose:

    • To provide a comprehensive analysis of current research on stress-induced upper gastrointestinal mucosal diseases.
    • To review the available drug prevention strategies for these complications.
    • To highlight knowledge gaps and controversies, particularly in urological patient populations.

    Summary:

    • This article synthesizes Russian and international studies on the epidemiology, clinical presentation, pathogenesis, and risk factors of stress-induced upper gastrointestinal mucosal diseases.
    • It evaluates various drug classes suitable for preventing these complications.
    • The review underscores the difficulties in selecting specific drugs due to incomplete understanding and limited, controversial data on these issues in urology patients.

    Impact:

    • Informs clinicians about the current understanding of stress-induced gastrointestinal mucosal damage.
    • Guides the selection of preventive pharmacotherapies.
    • Identifies critical areas for future research, especially concerning urological patient profiles.