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Heart rate variations in chronic obstructive pulmonary disease.
M Roca1, F Mitu2, Iulia-Cristina Roca3
1University of Medicine and Pharmacy Grigore T. Popa, lasi.
Summary
Chronic obstructive pulmonary disease (COPD) patients exhibit higher heart rates at rest and during exercise, indicating increased cardiovascular risk. Hypoxemia and resting heart rate influence exercise response in these patients.
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Area of Science:
- Cardiology
- Pulmonology
- Physiology
Background:
- Autonomic nervous system dysfunction is observed in chronic obstructive pulmonary disease (COPD) patients.
- This dysfunction may elevate cardiovascular risk through heart rate alterations.
Purpose of the Study:
- To investigate heart rate characteristics in COPD patients.
- To assess heart rate as a potential cardiovascular risk factor in COPD.
Main Methods:
- A prospective, case-control study compared 32 COPD patients and 29 healthy controls.
- Pulse rate was continuously recorded using a polygraph during rest and a 6-minute walk test.
- The relationship between pulse rate and respiratory, functional, or clinical factors was analyzed in COPD patients.
Main Results:
- COPD patients had significantly higher mean pulse rates at rest and during exercise compared to controls.
- Chronotropic response to exercise was similar between COPD patients and controls.
- Mean exercise pulse rate correlated with hypoxemia and resting pulse rate.
Conclusions:
- COPD is associated with elevated pulse rates during rest and exercise.
- Hypoxemia and resting pulse rate are key determinants of chronotropic response during submaximal exercise in COPD patients.