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Related Concept Videos

Diabetes Mellitus: Introduction01:26

Diabetes Mellitus: Introduction

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Diabetes mellitus consists of chronic metabolic disorders characterized by persistent hyperglycemia. This elevated blood glucose results from defects in insulin secretion, impaired insulin action, or both. Insulin, produced by pancreatic β-cells, is essential for maintaining glucose homeostasis by facilitating cellular glucose uptake for energy or storage. Disruptions in insulin production or function lead to glucose accumulation in the bloodstream, causing the clinical features and...
24
Type I Diabetes I: Introduction01:12

Type I Diabetes I: Introduction

45
Type 1 diabetes mellitus is a chronic metabolic disorder characterized by an absolute deficiency of insulin resulting from the autoimmune destruction of pancreatic β-cells. Although it can occur at any age, it is most commonly diagnosed in childhood, adolescence, or early adulthood. The loss of insulin production impairs cellular glucose uptake, resulting in persistent hyperglycemia and necessitating lifelong insulin therapy.Autoimmune Destruction of β-CellsThe hallmark of type 1...
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Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

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Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
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Type II Diabetes I: Introduction01:26

Type II Diabetes I: Introduction

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Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance, in which target tissues such as the liver, muscle, and adipose tissue respond poorly to insulin. It is also associated with inadequate compensatory insulin secretion, where pancreatic β-cells fail to produce sufficient insulin. Together, these abnormalities lead to persistent hyperglycemia.EtiologyT2DM develops through a complex interaction of genetic predisposition and environmental or...
17
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

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Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
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Type II Diabetes II: Pathophysiology01:24

Type II Diabetes II: Pathophysiology

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PathophysiologyType 2 diabetes mellitus (T2DM ) is a chronic metabolic disorder characterized by insulin resistance and progressive pancreatic β-cell dysfunction, leading to impaired glucose homeostasis. It results from interactions among genetic predisposition, environmental factors, and metabolic stressors, such as overnutrition and a sedentary lifestyle.Insulin Resistance and Glucose DysregulationEarly T2DM involves insulin resistance in skeletal muscle, adipose tissue, and the liver.
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Updated: May 3, 2026

High Resolution 3D Imaging of the Human Pancreas Neuro-insular Network
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Diabetes Interactive Atlas.

Karen A Kirtland1, Nilka R Burrows2, Linda S Geiss2

  • 1Northrop Grumman, 3375 Northeast Expressway NE, Atlanta, GA 30341.

Preventing Chronic Disease
|February 8, 2014
PubMed
Summary
This summary is machine-generated.

The Diabetes Interactive Atlas visualizes geographic trends in diabetes and its risk factors. This web-based tool enhances understanding of the disease

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Area of Science:

  • Public Health
  • Geographic Information Systems (GIS)
  • Epidemiology

Background:

  • Diabetes prevalence and risk factors exhibit significant geographic variation.
  • Understanding spatial-temporal trends is crucial for targeted public health interventions.
  • Existing data visualization tools may not adequately capture complex geographic patterns of diabetes.

Purpose of the Study:

  • To introduce the Diabetes Interactive Atlas, a novel web-based tool.
  • To describe the design and technical considerations for developing the atlas.
  • To showcase the atlas's capabilities in visualizing diabetes-related data.

Main Methods:

  • Development of a web-based platform integrating diverse data sources.
  • Implementation of interactive maps, tables, graphs, and motion charts.
  • Utilizing GIS to display national, state, and county-level data.

Main Results:

  • The atlas provides a comprehensive view of geographic patterns in diabetes and risk factors.
  • It enables simultaneous visualization of large datasets in multiple formats.
  • Demonstrates the geographic and temporal correlation between diabetes and obesity.

Conclusions:

  • The Diabetes Interactive Atlas significantly enhances the visualization of geographic patterns in diabetes.
  • It facilitates the observation of trends and the understanding of diabetes and obesity growth.
  • This tool supports public health research and decision-making by improving data accessibility and interpretation.