[Nalbuphine in pediatric anesthesia]
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Updated: May 3, 2026

Guidelines for Elective Pediatric Fiberoptic Intubation
Published on: January 17, 2011
A-M Schultz-Machata1, K Becke, M Weiss
1Universitätsklinik für Anästhesie, Allgemeine Intensivmedizin und Schmerztherapie, Klinische Abteilung für allgemeine Anästhesie und Intensivmedizin, Medizinische Universität Wien, 1090, Wien, Österreich, anette-marie.schultz@meduniwien.ac.at.
Abstract:
Efficient and safe pediatric perioperative pain therapy in the context of a multimodal pain therapy concept requires a slight to moderate opioid analgesic. Nalbuphine is a nearly ideal opioid for this purpose due to its unique pharmacological properties as a μ-receptor antagonist/κ-receptor agonist and a high safety profile. Nalbuphine is used clinically primarily in postoperative pain therapy administered as a bolus, continuous infusion and patient-controlled analgesia. Furthermore, it is administered in different regimens for pediatric diagnostic and interventional sedation.
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